This will be Liverpool's fourth meeting with Leeds in the League Cup, having won two and drawn one of the previous three.
Leeds have lost nine of their last 11 League Cup games against Premier League opposition (W2), including each of the four away games within this period.
The Reds have progressed from each of their last three League Cup quarter-finals, scoring 11 goals in the process (3.7 per game).
The Whites have featured in the League Cup quarter-final on seven occasions in their history (W5 L2), though just once post-2000 (in a 5-1 defeat v Chelsea in 2012/13).
24 of Liverpool's last 28 games against Leeds have taken place in the Premier League, where the Reds' 14 wins is the most inflicted on the Yorkshire side in competition history.
Jurgen Klopp has won six of his eight League Cup games in charge of Liverpool (D1 L1), and is looking to take his side into the semi-final for the second time in as many seasons.
